Mandatory expectation for all roles as per Syngene safety guidelines:
- Overall adherence to safe practices and procedures of oneself and the teams aligned
- Contributing to development of procedures, practices and systems that ensures safe operations and compliance to company’s integrity & quality standards
- Driving a corporate culture that promotes environment, health, and safety (EHS) mindset and operational discipline at the workplace at all times.
- Ensuring safety of self, teams and lab/plant by adhering to safety protocols and following environment, health, and safety (EHS) requirements at all times in the workplace.
- Ensure all assigned mandatory trainings related to data integrity, health, and safety measures are completed on time by all members of the team including self
- Compliance to Syngene’ s quality standards at all times
- Hold self and their teams accountable for the achievement of safety goals
- Govern and Review safety metrics from time to time
- Excellent time management and organizational skills, and attention to detail.
- Ability to work independently and as part of a team, self-motivation, adaptability.
- Must have a high moral framework (ethics code) and high sense of data integrity values.
- Excellence
- Integrity
- Professionalism
- Champion effective Environment, Occupational Health, Safety and Sustainability (EHSS) practices for the company and oversee compliance with those practices within Biologics business. Play an active leadership role in monitoring and verifying safety performance through Gemba walks and other safety-led activities.
- Foster a corporate culture that promotes an environment, occupational health, safety, and sustainability (EHSS) mindset as well as the highest standards of quality, integrity, and compliance.
- Put people at the heart of our success by providing clear, active leadership defined by the Syngene leadership framework setting high standards of people management, career planning and talent retention as a priority.
- Comprehensive theoretical and practical knowledge and experience in mammalian and microbial (desirable) recombinant protein purification techniques (including affinity, ion exchange, HIC, SEC, CHT and reverse phase chromatography, TFF) and methods development. Candidates having demonstrated hands-on experience in both mammalian and microbial projects will be preferred.
- Should have experience in analytical biochemistry (SEC-HPLC, SEC-MALS/DLS, SDS PAGE, Western Blot, Protein quantification etc.)
- Strong FPLC/liquid chromatography experience – ability to program, operate, and troubleshoot purification equipment and experiments at small/pilot scale using the GE AKTA platform including AKTA PURE, Pilot, Explorer.
- DoE based process development.
- Ability to learn new techniques, perform multiple tasks simultaneously, update technical data and maintain accurate records contemporaneously, follow instructions, and comply with company policies.
- Work according to established Standard Operating Procedure (SOP) and regulatory guidance.
- Should have excellent oral, presentation and written communication skills: Team player and customer-focused
- Should have good publication record
- Apply mass spectrometry - based approaches, including intact mass, glycan profiling, glycosylation site and disulfide bond mapping, peptide mapping to support protein analysis and characterization.
- Additional advantage is having a demonstrated experience in optimising expression and purification of recombinant proteins from microbial source.
- Knowledge and experience in packing resins in columns like XK, HiScale and BPG.
- Knowledge in moderate throughput purification techniques (e.g-Magbeads, Coupled Columns) is desirable
